{"id":521,"count":1,"description":"<strong>Rosacea<\/strong> je charakterizovan\u00e1 chronick\u00fdm z\u00e1palov\u00fdm stavom, ktor\u00fd je hlavne vyvolan\u00fd nadmernou reakciou prirodzen\u00e9ho imunitn\u00e9ho syst\u00e9mu a oxidat\u00edvnym stresom. Postihuje 5% popul\u00e1cie.\r\n\r\nHlavn\u00e9 mechanizmy spojen\u00e9 s rozvojom rozacey a kuper\u00f3zy s\u00fa <strong>oxidat\u00edvny stres, z\u00e1pal, nerovnov\u00e1ha mikrofl\u00f3ry a zmeny \u0161truktur\u00e1lnych bielkov\u00edn v epiderme a derme.<\/strong> V\u0161etky tieto faktory s\u00fa zodpovedn\u00e9 za pr\u00edznaky a anatomick\u00e9 zmeny spojen\u00e9 s touto chorobou: za\u010dervenanie, trval\u00e1 eryt\u00e9mia, citliv\u00e1 ko\u017ea, telangiekt\u00e1zie, papuly a pustuly. V oblastiach, kde choroba pretrv\u00e1va dlh\u0161\u00ed \u010das, sa m\u00f4\u017eu vyvin\u00fa\u0165 \u017elto-oran\u017eov\u00e9 plaky v d\u00f4sledku seb\u00f3znej hyperpl\u00e1zie, naj\u010dastej\u0161ie na nose (rinof\u00fdma).\r\n\r\nNed\u00e1vne \u0161t\u00fadie uk\u00e1zali, \u017ee glutation hr\u00e1 k\u013e\u00fa\u010dov\u00fa \u00falohu ako hlavn\u00e1 intracelul\u00e1rna antioxida\u010dn\u00e1 molekula. Pri rosacei doch\u00e1dza k nedostatku intracelul\u00e1rneho glutationu, \u010do zni\u017euje antioxida\u010dn\u00e9 obrann\u00e9 mechanizmy buniek. Zv\u00fd\u0161en\u00fd oxidat\u00edvny stres je zodpovedn\u00fd za zv\u00fd\u0161en\u00fd z\u00e1palov\u00fd stav, ktor\u00fd sp\u00f4sobuje klinick\u00fd obraz. \r\n\r\nCie\u013eom lie\u010dby rosacey je zmierni\u0165 <strong>pr\u00edznaky a zlep\u0161i\u0165 soci\u00e1lno-psychologick\u00fd aspekt.<\/strong> Na z\u00e1klade nov\u00fdch vedeck\u00fdch d\u00f4kazov m\u00f4\u017ee posilnenie bunkov\u00fdch antioxida\u010dn\u00fdch obrann\u00fdch mechanizmov predstavova\u0165 nov\u00fd a \u00fa\u010dinn\u00fd pr\u00edstup k lie\u010dbe.","link":"https:\/\/difacooper.eu\/sk\/therapeutic-area\/rozacea\/","name":"ROZACEA","slug":"rozacea","taxonomy":"therapeutic-area","parent":0,"meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ROZACEA Archives - Cantabrialabs Difa Cooper<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/difacooper.eu\/sk\/therapeutic-area\/rozacea\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ROZACEA Archives - Cantabrialabs Difa Cooper\" \/>\n<meta property=\"og:description\" content=\"Rosacea je charakterizovan\u00e1 chronick\u00fdm z\u00e1palov\u00fdm stavom, ktor\u00fd je hlavne vyvolan\u00fd nadmernou reakciou prirodzen\u00e9ho imunitn\u00e9ho syst\u00e9mu a oxidat\u00edvnym stresom. Postihuje 5% popul\u00e1cie. Hlavn\u00e9 mechanizmy spojen\u00e9 s rozvojom rozacey a kuper\u00f3zy s\u00fa oxidat\u00edvny stres, z\u00e1pal, nerovnov\u00e1ha mikrofl\u00f3ry a zmeny \u0161truktur\u00e1lnych bielkov\u00edn v epiderme a derme. V\u0161etky tieto faktory s\u00fa zodpovedn\u00e9 za pr\u00edznaky a anatomick\u00e9 zmeny spojen\u00e9 s touto chorobou: za\u010dervenanie, trval\u00e1 eryt\u00e9mia, citliv\u00e1 ko\u017ea, telangiekt\u00e1zie, papuly a pustuly. V oblastiach, kde choroba pretrv\u00e1va dlh\u0161\u00ed \u010das, sa m\u00f4\u017eu vyvin\u00fa\u0165 \u017elto-oran\u017eov\u00e9 plaky v d\u00f4sledku seb\u00f3znej hyperpl\u00e1zie, naj\u010dastej\u0161ie na nose (rinof\u00fdma). Ned\u00e1vne \u0161t\u00fadie uk\u00e1zali, \u017ee glutation hr\u00e1 k\u013e\u00fa\u010dov\u00fa \u00falohu ako hlavn\u00e1 intracelul\u00e1rna antioxida\u010dn\u00e1 molekula. Pri rosacei doch\u00e1dza k nedostatku intracelul\u00e1rneho glutationu, \u010do zni\u017euje antioxida\u010dn\u00e9 obrann\u00e9 mechanizmy buniek. Zv\u00fd\u0161en\u00fd oxidat\u00edvny stres je zodpovedn\u00fd za zv\u00fd\u0161en\u00fd z\u00e1palov\u00fd stav, ktor\u00fd sp\u00f4sobuje klinick\u00fd obraz. Cie\u013eom lie\u010dby rosacey je zmierni\u0165 pr\u00edznaky a zlep\u0161i\u0165 soci\u00e1lno-psychologick\u00fd aspekt. Na z\u00e1klade nov\u00fdch vedeck\u00fdch d\u00f4kazov m\u00f4\u017ee posilnenie bunkov\u00fdch antioxida\u010dn\u00fdch obrann\u00fdch mechanizmov predstavova\u0165 nov\u00fd a \u00fa\u010dinn\u00fd pr\u00edstup k lie\u010dbe.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/difacooper.eu\/sk\/therapeutic-area\/rozacea\/\" \/>\n<meta property=\"og:site_name\" content=\"Cantabrialabs Difa Cooper\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"CollectionPage\",\"@id\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/therapeutic-area\\\/rozacea\\\/\",\"url\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/therapeutic-area\\\/rozacea\\\/\",\"name\":\"ROZACEA Archives - Cantabrialabs Difa Cooper\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/#website\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/therapeutic-area\\\/rozacea\\\/#breadcrumb\"},\"inLanguage\":\"sk-SK\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/therapeutic-area\\\/rozacea\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"ROZACEA\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/#website\",\"url\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/\",\"name\":\"Cantabrialabs Difa Cooper\",\"description\":\"Research and innovation at the service of dermatology\",\"publisher\":{\"@id\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"sk-SK\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/#organization\",\"name\":\"Cantabrialabs Difa Cooper\",\"url\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"sk-SK\",\"@id\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/difacooper.eu\\\/wp-content\\\/uploads\\\/difacooper-logo-bianco.png\",\"contentUrl\":\"https:\\\/\\\/difacooper.eu\\\/wp-content\\\/uploads\\\/difacooper-logo-bianco.png\",\"width\":512,\"height\":100,\"caption\":\"Cantabrialabs Difa Cooper\"},\"image\":{\"@id\":\"https:\\\/\\\/difacooper.eu\\\/sk\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"ROZACEA Archives - Cantabrialabs Difa Cooper","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/difacooper.eu\/sk\/therapeutic-area\/rozacea\/","og_locale":"sk_SK","og_type":"article","og_title":"ROZACEA Archives - Cantabrialabs Difa Cooper","og_description":"Rosacea je charakterizovan\u00e1 chronick\u00fdm z\u00e1palov\u00fdm stavom, ktor\u00fd je hlavne vyvolan\u00fd nadmernou reakciou prirodzen\u00e9ho imunitn\u00e9ho syst\u00e9mu a oxidat\u00edvnym stresom. 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