{"id":576,"count":1,"description":"Rozaceea se caracterizeaz\u0103 printr-o stare inflamatorie cronic\u0103 declan\u0219at\u0103 \u00een principal de un r\u0103spuns imun \u00eenn\u0103scut exagerat \u0219i de stresul oxidativ. Afecteaz\u0103 aproximativ 5% din popula\u021bia general\u0103.\r\nPrincipalele mecanisme implicate \u00een rozacee \u0219i cuperoz\u0103 sunt stresul oxidativ, inflama\u021bia, dezechilibrul microbiomului \u0219i alterarea proteinelor structurale ale epidermei \u0219i dermului; toate acestea fiind responsabile pentru semnele \u0219i modific\u0103rile anatomice ale acestei afec\u021biuni: ro\u0219ea\u021b\u0103 tranzitorie, eritem persistent, piele sensibil\u0103, telangiectazii, papule \u0219i pustule. \u00cen zonele \u00een care afec\u021biunea este veche pot ap\u0103rea pl\u0103ci galben-portocalii, ca urmare a hiperplaziei sebacee, cel mai frecvent la nivelul nasului (rinofima).\r\nStudii recente au demonstrat c\u0103 glutationul joac\u0103 un rol esen\u021bial ca principala molecul\u0103 antioxidant\u0103 intracelular\u0103. \u00cen cazul rozaceei, exist\u0103 un deficit de glutation intracelular care reduce capacitatea celulelor de a se ap\u0103ra \u00eempotriva stresului oxidativ. Acest stres oxidativ crescut este responsabil de amplificarea st\u0103rii inflamatorii care genereaz\u0103 tabloul clinic.\r\nGestionarea rozaceei urm\u0103re\u0219te reducerea semnelor \u0219i simptomelor \u0219i \u00eembun\u0103t\u0103\u021birea aspectului socio-psihologic al pacientului. Pe baza noilor dovezi \u0219tiin\u021bifice, \u00eent\u0103rirea ap\u0103r\u0103rii antioxidante celulare poate reprezenta o abordare nou\u0103 \u0219i eficient\u0103 de tratament.\r\n<ul>\r\n \t<li>Eutrosis AR<\/li>\r\n<\/ul>","link":"https:\/\/difacooper.eu\/ro\/therapeutic-area\/rozaceea\/","name":"Rozaceea","slug":"rozaceea","taxonomy":"therapeutic-area","parent":0,"meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Rozaceea Archives - Cantabrialabs Difa Cooper<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/difacooper.eu\/ro\/therapeutic-area\/rozaceea\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Rozaceea Archives - Cantabrialabs Difa Cooper\" \/>\n<meta property=\"og:description\" content=\"Rozaceea se caracterizeaz\u0103 printr-o stare inflamatorie cronic\u0103 declan\u0219at\u0103 \u00een principal de un r\u0103spuns imun \u00eenn\u0103scut exagerat \u0219i de stresul oxidativ. Afecteaz\u0103 aproximativ 5% din popula\u021bia general\u0103. Principalele mecanisme implicate \u00een rozacee \u0219i cuperoz\u0103 sunt stresul oxidativ, inflama\u021bia, dezechilibrul microbiomului \u0219i alterarea proteinelor structurale ale epidermei \u0219i dermului; toate acestea fiind responsabile pentru semnele \u0219i modific\u0103rile anatomice ale acestei afec\u021biuni: ro\u0219ea\u021b\u0103 tranzitorie, eritem persistent, piele sensibil\u0103, telangiectazii, papule \u0219i pustule. \u00cen zonele \u00een care afec\u021biunea este veche pot ap\u0103rea pl\u0103ci galben-portocalii, ca urmare a hiperplaziei sebacee, cel mai frecvent la nivelul nasului (rinofima). Studii recente au demonstrat c\u0103 glutationul joac\u0103 un rol esen\u021bial ca principala molecul\u0103 antioxidant\u0103 intracelular\u0103. \u00cen cazul rozaceei, exist\u0103 un deficit de glutation intracelular care reduce capacitatea celulelor de a se ap\u0103ra \u00eempotriva stresului oxidativ. Acest stres oxidativ crescut este responsabil de amplificarea st\u0103rii inflamatorii care genereaz\u0103 tabloul clinic. Gestionarea rozaceei urm\u0103re\u0219te reducerea semnelor \u0219i simptomelor \u0219i \u00eembun\u0103t\u0103\u021birea aspectului socio-psihologic al pacientului. Pe baza noilor dovezi \u0219tiin\u021bifice, \u00eent\u0103rirea ap\u0103r\u0103rii antioxidante celulare poate reprezenta o abordare nou\u0103 \u0219i eficient\u0103 de tratament. Eutrosis AR\" \/>\n<meta property=\"og:url\" content=\"https:\/\/difacooper.eu\/ro\/therapeutic-area\/rozaceea\/\" \/>\n<meta property=\"og:site_name\" content=\"Cantabrialabs Difa Cooper\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"CollectionPage\",\"@id\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/therapeutic-area\\\/rozaceea\\\/\",\"url\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/therapeutic-area\\\/rozaceea\\\/\",\"name\":\"Rozaceea Archives - Cantabrialabs Difa Cooper\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/#website\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/therapeutic-area\\\/rozaceea\\\/#breadcrumb\"},\"inLanguage\":\"ro-RO\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/therapeutic-area\\\/rozaceea\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Rozaceea\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/#website\",\"url\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/\",\"name\":\"Cantabrialabs Difa Cooper\",\"description\":\"Research and innovation at the service of dermatology\",\"publisher\":{\"@id\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ro-RO\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/#organization\",\"name\":\"Cantabrialabs Difa Cooper\",\"url\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ro-RO\",\"@id\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/difacooper.eu\\\/wp-content\\\/uploads\\\/difacooper-logo-bianco.png\",\"contentUrl\":\"https:\\\/\\\/difacooper.eu\\\/wp-content\\\/uploads\\\/difacooper-logo-bianco.png\",\"width\":512,\"height\":100,\"caption\":\"Cantabrialabs Difa Cooper\"},\"image\":{\"@id\":\"https:\\\/\\\/difacooper.eu\\\/ro\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Rozaceea Archives - Cantabrialabs Difa Cooper","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/difacooper.eu\/ro\/therapeutic-area\/rozaceea\/","og_locale":"ro_RO","og_type":"article","og_title":"Rozaceea Archives - Cantabrialabs Difa Cooper","og_description":"Rozaceea se caracterizeaz\u0103 printr-o stare inflamatorie cronic\u0103 declan\u0219at\u0103 \u00een principal de un r\u0103spuns imun \u00eenn\u0103scut exagerat \u0219i de stresul oxidativ. 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Acest stres oxidativ crescut este responsabil de amplificarea st\u0103rii inflamatorii care genereaz\u0103 tabloul clinic. Gestionarea rozaceei urm\u0103re\u0219te reducerea semnelor \u0219i simptomelor \u0219i \u00eembun\u0103t\u0103\u021birea aspectului socio-psihologic al pacientului. Pe baza noilor dovezi \u0219tiin\u021bifice, \u00eent\u0103rirea ap\u0103r\u0103rii antioxidante celulare poate reprezenta o abordare nou\u0103 \u0219i eficient\u0103 de tratament. 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